| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ACE2 |
| Specificity: |
This antibody reacts specifically with ACE2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ACE2 |
| Gene ID: |
59272 |
| Swiss Prot: |
Q9BYF1 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Pig/Swine (Sus scrofa), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency, In case of human coronaviruses SARS and HCoV-NL63 infections, May be an important regulator of heart function, a peptide of unknown function, a vasodilator, and angiotensin II to angiotensin 1-7, serve as functional receptor for the spike glycoprotein of both coronaviruses, Carboxypeptidase which converts angiotensin I to angiotensin 1-9 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
ACE2 Polyclonal Antibody |
| Other name: |
Anti-ACE2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ACE2 |
| Short name: |
Anti-ACE2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ACE2 and IDBG-46534 and ENSG00000130234 and 59272, ACE2 and IDBG-638902 and ENSBTAG00000034402 and 101908244, Ace2 and IDBG-184519 and ENSMUSG00000015405 and 70008, Extracellular, peptide binding, this GO :0001618 and virus receptor activity and molecular function this GO :0001817 and regulation of cytokine production and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0002003 and angiotensin maturation and biological process this GO :0002005 and angiotensin catabolic process in blood and biological process this GO :0003051 and angiotensin-mediated drinking behavior and biological process this GO :0003081 and regulation of systemic arterial blood pressure by renin-angiotensin and biological process this GO :0004175 and endopeptidase activity and molecular function this GO :0004180 and carboxypeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0008237 and metallopeptidase activity and molecular function this GO :0008241 and peptidyl-dipeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0009615 and response to virus and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017046 and peptide hormone binding and molecular function this GO :0019229 and regulation of vasoconstriction and biological process this GO :0032800 and receptor biosynthetic process and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042277 and peptide binding and molecular function this GO :0042312 and regulation of vasodilation and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0046718 and viral entry into host cell and biological process this GO :0046813 and receptor-mediated virion attachment to host cell and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0060135 and maternal process involved in female pregnancy and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process, this GO :0001618 : virus receptor activity, this GO :0001618 : virus receptor activity and also this GO :0001948 : glycoprotein binding and also this GO :0004175 : endopeptidase activity and also this GO :0004180 : carboxypeptidase activity and also this GO :0005515 : protein binding and also this GO :0008237 : metallopeptidase activity and also this GO :0008241 : peptidyl-dipeptidase activity and also this GO :0008270 : zinc ion binding and also this GO :0017046 : peptide hormone binding and also this GO :0042277 : peptide binding, this GO :0001948 : glycoprotein binding, this GO :0004175 : endopeptidase activity, this GO :0004180 : carboxypeptidase activity, this GO :0005515 : protein binding, this GO :0008237 : metallopeptidase activity, this GO :0008241 : peptidyl-dipeptidase activity, this GO :0008270 : zinc ion binding, this GO :0017046 : peptide hormone binding, this GO :0042277 : peptide binding, 509235, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| Identity: |
13557 |
| Gene: |
ACE2 |
More about : ACE2 |
| Long gene name: |
angiotensin I converting enzyme 2 |
| Synonyms gene name: |
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| Synonyms name: |
peptidyl-dipeptidase A |
| Locus: |
Xp22, 2 |
| Discovery year: |
2000-09-25 |
| GenBank acession: |
AF291820 |
| Entrez gene record: |
59272 |
| Pubmed identfication: |
10969042 |
| Havana BLAST/BLAT: |
OTTHUMG00000021177 |
| Locus Specific Databases: |
Mental Retardation database |