| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Adrenomedullin |
| Specificity: |
This antibody reacts specifically with Adrenomedullin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ADM |
| Gene ID: |
133 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ADM has strong natriuretic actions, ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning, ADM is present both in the periphery and brain, ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption, In hypertensive patients, Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage, a vasodilator produced by most contractile cells, and can exert central effects such as decreasing food ingestion, is characterized by persistent hypotensive activity, the level of ADM in plasma is up-regulated, Adrenomedullin (ADM) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AM |
| Also known as: |
Adrenomedullin Polyclonal Antibody |
| Other name: |
Anti-Adrenomedullin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Adrenomedullin |
| Short name: |
Anti-Adrenomedullin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Adrenomedullin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
259 |
| Gene: |
ADM |
More about : ADM |
| Long gene name: |
adrenomedullin |
| Locus: |
11p15, 4 |
| Discovery year: |
1994-12-15 |
| GenBank acession: |
D14874 |
| Entrez gene record: |
133 |
| Pubmed identfication: |
7688224 |
| RefSeq identity: |
NM_001124 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000165907 |