| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Alpha-Synuclein |
| Specificity: |
This antibody reacts specifically with Alpha-Synuclein |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
Recombinant full length Alpha-Synuclein |
| Gene ID: |
6622 |
| Swiss Prot: |
P37840 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Induces fibrillization of microtubule-associated protein tau, Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation, May be involved in the regulation of dopamine release and transport |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NACP PD1 alpha-synuclein |
| Also known as: |
Alpha-Synuclein Polyclonal Antibody |
| Other name: |
Anti-Alpha-Synuclein Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Description: |
- or alpha protein sometimes glycoprotein present in blood, The Anti-Alpha-Synuclein (Polyclonal) Fluor 594 is a &alpha |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Alpha-Synuclein |
| Short name: |
Anti-Alpha-Synuclein (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-a-Synuclein (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11138 |
| Gene: |
SNCA |
More about : SNCA |
| Long gene name: |
synuclein alpha |
| Synonyms gene: |
PARK1 PARK4 |
| Synonyms gene name: |
Lewy body) 4 synuclein, Parkinson disease (autosomal dominant, alpha (non A4 component of amyloid precursor) |
| Synonyms name: |
non A4 component of amyloid precursor |
| Locus: |
4q22, 1 |
| Discovery year: |
1995-01-24 |
| GenBank acession: |
L08850 |
| Entrez gene record: |
6622 |
| Pubmed identfication: |
8248242 14593171 |
| Classification: |
Parkinson disease associated genes |
| Havana BLAST/BLAT: |
OTTHUMG00000130948 |
| Locus Specific Databases: |
Parkinson', s disease Mutation Database |