| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CA3 / Carbonic Anhydrase III |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, IHC (FFPE): 1-2ug/ml, Western blot: 0 |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This CA3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P07451 |
| Purity: |
Antigen affinity |
| Description: |
A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal, CA3 is a member of a multigene family (at least six separate genes are known) that encode carbonic anhydrase isozymes, The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle, The gene spans 10, Using a cDNA clone of the CA3 gene in the study of human-rodent hybrids, the gene was mapped to chromosome 8 which carries a cluster of CA genes, 3 kb and contains seven exons and six introns, Carbonic Anhydrase III (CA3) is an enzyme that in humans is encoded by the CA3 gene |
| Immunogen: |
Amino acids D14-E235 from the human protein were used as the immunogen for the CA3 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CA3 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CA3 / Carbonic Anhydrase III |
| Short name: |
CA3 Antibody / Carbonic Anhydrase III |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CA3 (Antibody to) / Carbonic Anhydrase III |
| Alternative technique: |
antibodies |
| Identity: |
1374 |
| Gene: |
CA3 |
More about : CA3 |
| Long gene name: |
carbonic anhydrase 3 |
| Synonyms gene name: |
carbonic anhydrase III, muscle specific carbonic anhydrase III |
| Synonyms: |
Car3 CAIII |
| Locus: |
8q21, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
AJ006473 |
| Entrez gene record: |
761 |
| Pubmed identfication: |
6221502 |
| RefSeq identity: |
NM_005181 |
| Classification: |
Carbonic anhydrases |
| Havana BLAST/BLAT: |
OTTHUMG00000164942 |