| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AKR1B1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, IHC (FFPE): 1-2ug/ml, Western blot: 0 |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This AKR1B1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P15121 |
| Purity: |
Antigen affinity |
| Description: |
This gene encodes a member of the aldo/keto reductase superfamily, This member catalyzes the reduction of a number ofaldehydes, also known as AR, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol, including the aldehyde form of glucose, is an enzyme that in humans is encoded by the AKR1B1 gene, member B1 (aldose reductase), which consists of more than 40 known enzymes and proteins, Aldo-keto reductase family 1 |
| Immunogen: |
Amino acids L228-F316 from the human protein were used as the immunogen for the AKR1B1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the AKR1B1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
nuclear, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AKR1B1 |
| Short name: |
AKR1B1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AKR1B1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
381 |
| Gene: |
AKR1B1 |
More about : AKR1B1 |
| Long gene name: |
aldo-keto reductase family 1 member B |
| Synonyms gene: |
ALDR1 |
| Synonyms gene name: |
aldo-keto reductase family 1, member B1 (aldose reductase) |
| Synonyms: |
AR |
| Synonyms name: |
aldose reductase |
| Locus: |
7q33 |
| Discovery year: |
1991-08-07 |
| GenBank acession: |
J04795 |
| Entrez gene record: |
231 |
| Pubmed identfication: |
1901827 |
| RefSeq identity: |
NM_001628 |
| Classification: |
Aldo-keto reductases |
| Havana BLAST/BLAT: |
OTTHUMG00000155322 |