| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ADAMTS13 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA (protein), WB |
| Recommended dilutions: |
request BSA-free format for coating, 5-1ug/ml, 5-1ug/ml (human protein tested), ELISA: 0, Western blot: 0 |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This ADAMTS13 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q76LX8 |
| Purity: |
Antigen affinity |
| Description: |
It is secreted in blood and degrades large vWf multimers, This gene encodes a member of a family of proteins containing several distinct regions, This gene is mapped to 9q34, a disintegrin-like domain, a large protein involved in blood clotting, also known as VWFCP, and a thrombospondin type 1 (TS) motif, decreasing their activity, including a metalloproteinase domain, is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), member 13), ADAMTS13 (A disintegrin and metalloproteinase with athrombospondin type 1 motif |
| Immunogen: |
Amino acids A299-R488 from the human protein were used as the immunogen for the ADAMTS13 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ADAMTS13 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ADAMTS13 |
| Short name: |
ADAMTS13 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
13 (Antibody to), ADAM metallopeptidase including thrombospondin classification 1 motif |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
13, ADAM-TS13 and ADAMTS-13 and C9orf8 and vWF-CP and VWFCP, ADAMTS13 and IDBG-640733 and ENSBTAG00000015093 and, ADAMTS13 and IDBG-91330 and ENSG00000160323 and 11093, Adamts13 and IDBG-150457 and ENSMUSG00000014852 and 279028, Extracellular, this GO :0004175 and endopeptidase activity and molecular function this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006508 and proteolysis and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008233 and peptidase activity and molecular function this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0009100 and glycoprotein metabolic process and biological process this GO :0009636 and response to toxic substance and biological process this GO :0009986 and cell surface and cellular component this GO :0016485 and protein processing and biological process this GO :0030168 and platelet activation and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0034341 and response to interferon-gamma and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0043171 and peptide catabolic process and biological process this GO :0070670 and response to interleukin-4 and biological process, this GO :0004175 : endopeptidase activity, this GO :0004175 : endopeptidase activity and also this GO :0004222 : metalloendopeptidase activity and also this GO :0005178 : integrin binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008233 : peptidase activity and also this GO :0008237 : metallopeptidase activity and also this GO :0008270 : zinc ion binding, this GO :0004222 : metalloendopeptidase activity, this GO :0005178 : integrin binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008233 : peptidase activity, this GO :0008237 : metallopeptidase activity, this GO :0008270 : zinc ion binding, zinc ion binding, ADAM metallopeptidase with thrombospondin type 1 motif |
| Identity: |
1366 |
| Gene: |
ADAMTS13 |
More about : ADAMTS13 |
| Long gene name: |
ADAM metallopeptidase with thrombospondin type 1 motif 13 |
| Synonyms gene: |
C9orf8 |
| Synonyms gene name: |
13 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif |
| Synonyms: |
VWFCP TTP vWF-CP FLJ42993 MGC118899 MGC118900 DKFZp434C2322 |
| Locus: |
9q34, 2 |
| Discovery year: |
1999-08-23 |
| GenBank acession: |
AJ011374 |
| Entrez gene record: |
11093 |
| Pubmed identfication: |
11557746 11535495 |
| RefSeq identity: |
NM_139025 |
| Classification: |
ADAM metallopeptidases with thrombospondin type 1 motif |
| Havana BLAST/BLAT: |
OTTHUMG00000020876 |
| Locus Specific Databases: |
LRG_544 |