| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ABCE1 / ATP binding cassette E1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This ABCE1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P61221 |
| Purity: |
Antigen affinity |
| Description: |
ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, ABCE1 inhibits the action of ribonuclease L, It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis, It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily, Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2', also RNase L inhibitor) is an ATPase found in humans involved in viral assembly, and allow the virus to synthesize viral proteins, antagonizing the anti-viral properties of ribonuclease L, which is used by viruses, 5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, ATP binding cassette E1 (ABCE1 |
| Immunogen: |
Amino acids K419-D599 from the human protein were used as the immunogen for the ABCE1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ABCE1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ABCE1 / ATP binding cassette E1 |
| Short name: |
ABCE1 Antibody / ATP binding cassette E1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ABCE1 (Antibody to) / adenosine triphosphate binding cassette E1 |
| Alternative technique: |
antibodies |
| Identity: |
69 |
| Gene: |
ABCE1 |
More about : ABCE1 |
| Long gene name: |
ATP binding cassette subfamily E member 1 |
| Synonyms gene: |
RNASEL1 RNASELI RNS4I |
| Synonyms gene name: |
ATP-binding cassette, member 1 , sub-family E (OABP) |
| Synonyms: |
RLI OABP RLI1 |
| Synonyms name: |
RNase L inhibitor 1 |
| Locus: |
4q31, 21 |
| Discovery year: |
1995-11-01 |
| GenBank acession: |
X74987 |
| Entrez gene record: |
6059 |
| Pubmed identfication: |
7539425 |
| RefSeq identity: |
NM_002940 |
| Classification: |
ATP binding cassette subfamily E |
| Havana BLAST/BLAT: |
OTTHUMG00000161478 |