| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Insulin |
| Specificity: |
This antibody reacts specifically with Insulin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
Recombinant human insulin |
| Gene ID: |
3630 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Heterodimer of a B chain and an A chain linked by two disulfide bonds, IGF-I and IGF-II (also desinated somatomedin C and multiplication stimulating activator, IGF-I functions as an autocrine regulator of growth in vaious, It accelerates glycolysis, It increases cell permeability to monosaccharides, The insulin-link growth factors, amino acids and fatty acids, and glycogen synthesis in liver, respectivelly, respectvely), share approximatly 76% sequence identity and are 50% related to pro-insulin, single chain proteins of 70 and 76 amino acids in length, the pentose phosphate cycle, whereas the function of IGF-II is less well defined, Belongs to the insulin family, IGF-I and IGF-II are nonglycosylated, Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of protein and fat |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Insulin Polyclonal Antibody |
| Other name: |
Anti-Insulin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Insulin |
| Short name: |
Anti-Insulin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Insulin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
5378 |
| Gene: |
IDDM7 |
More about : IDDM7 |
| Long gene name: |
insulin dependent diabetes mellitus 7 |
| Locus: |
2q31 |
| Discovery year: |
1994-11-08 |
| Pubmed identfication: |
7813807 |