| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AFG3L2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the AFG3L2 antibody should be determined by the researcher |
| Intented use: |
This AFG3L2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y4W6 |
| Purity: |
Antigen affinity |
| Description: |
And this gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy syndrome, In humans, The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia, This gene encodes a protein localized in mitochondria and closely related to paraplegin, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly, it is encoded by the AFG3L2 gene, AFG3L2 is the catalytic subunit of the m-AAA protease |
| Immunogen: |
Amino acids R168-D250 of the human protein were used as the immunogen for the AFG3L2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the AFG3L2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AFG3L2 |
| Short name: |
AFG3L2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AFG3L2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
315 |
| Gene: |
AFG3L2 |
More about : AFG3L2 |
| Long gene name: |
AFG3 like matrix AAA peptidase subunit 2 |
| Synonyms gene: |
SCA28 |
| Synonyms gene name: |
AFG3 (ATPase family gene 3, cerevisiae) AFG3 like AAA ATPase 2 , yeast)-like 2 spinocerebellar ataxia 28 AFG3 ATPase family member 3-like 2 (S |
| Synonyms: |
SPAX5 |
| Locus: |
18p11, 21 |
| Discovery year: |
1999-07-13 |
| GenBank acession: |
Y18314 |
| Entrez gene record: |
10939 |
| Pubmed identfication: |
10395799 18769991 |
| RefSeq identity: |
NM_006796 |
| Classification: |
AAA ATPases |
| Havana BLAST/BLAT: |
OTTHUMG00000131695 |
| Locus Specific Databases: |
LRG_666 |