| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PLZF / ZBTB16 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the PLZF antibody should be determined by the researcher |
| Intented use: |
This PLZF antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q05516 |
| Purity: |
Antigen affinity |
| Description: |
Alternate transcriptional splice variants have been characterized, Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL), This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus, This protein is located in the nucleus, and interacts with a histone deacetylase, is involved in cell cycle progression, Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene |
| Immunogen: |
Amino acids M1-E165 from the human protein were used as the immunogen for the PLZF antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PLZF antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PLZF / ZBTB16 |
| Short name: |
PLZF Antibody / ZBTB16 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PLZF (Antibody to) / zinc finger and BTB domain containing 16 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0007417 and central nervous system development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009880 and embryonic pattern specification and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016604 and nuclear body and cellular component this GO :0016605 and PML body and cellular component this GO :0016607 and nuclear speck and cellular component this GO :0017053 and transcriptional repressor complex and cellular component this GO :0019904 and protein domain specific binding and molecular function this GO :0030097 and hemopoiesis and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0032332 and positive regulation of chondrocyte differentiation and biological process this GO :0034504 and protein localization to nucleus and biological process this GO :0035116 and embryonic hindlimb morphogenesis and biological process this GO :0035136 and forelimb morphogenesis and biological process this GO :0035137 and hindlimb morphogenesis and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0045638 and negative regulation of myeloid cell differentiation and biological process this GO :0045778 and positive regulation of ossification and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048133 and male germ-line stem cell division and biological process this GO :0051138 and positive regulation of NK T cell differentiation and biological process this GO :0051216 and cartilage development and biological process this GO :0061036 and positive regulation of cartilage development and biological process, PLZF and ZNF145, ZBTB16 and IDBG-630682 and ENSBTAG00000011266 and 534401, ZBTB16 and IDBG-72004 and ENSG00000109906 and 7704, Zbtb16 and IDBG-162201 and ENSMUSG00000066687 and 235320, metal ion binding, nuclei, this GO :0001501 and skeletal system development and biological process this GO :0001823 and mesonephros development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008022 : protein C-terminus binding and also this GO :0019904 : protein domain specific binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046872 : metal ion binding, this GO :0003690 : double-stranded DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008022 : protein C-terminus binding, this GO :0019904 : protein domain specific binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0046872 : metal ion binding, zinc finger and BTB domain containing 16 |
| Identity: |
12930 |
| Gene: |
ZBTB16 |
More about : ZBTB16 |
| Long gene name: |
zinc finger and BTB domain containing 16 |
| Synonyms gene: |
ZNF145 |
| Synonyms gene name: |
expressed in promyelocytic leukemia) , zinc finger protein 145 (Kruppel-like |
| Synonyms: |
PLZF |
| Synonyms name: |
promyelocytic leukaemia zinc finger |
| Locus: |
11q23, 2 |
| Discovery year: |
1993-11-01 |
| GenBank acession: |
Z19002 |
| Entrez gene record: |
7704 |
| RefSeq identity: |
NM_006006 |
| Classification: |
BTB domain containing Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000168243 |