| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CGRP / CALCA |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
5-1ug/ml, IHC (FFPE): 0 |
| Notes: |
Optimal dilution of the CGRP antibody should be determined by the researcher |
| Intented use: |
This CGRP antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P06881 |
| Purity: |
Antigen affinity |
| Description: |
Calcitonin belongs to the calcitonin-like protein family, Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide, Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism, It is mapped to 11p15, Multiple transcript variants encoding different isoforms have been found for this gene, also known as CALCA, is a peptide hormone synthesized by the parafollicular cells of the thyroid, 2, Calcitonin gene-related peptide 1 |
| Immunogen: |
Amino acids ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF were used as the immunogen for the CGRP antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CGRP antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CGRP / CALCA |
| Short name: |
CGRP Antibody / CALCA |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CGRP (Antibody to) / calcitonin-related polypeptide a |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CALC1 and CGRP and CGRP-I and CGRP1 and CT and KC, CALCA and IDBG-33289 and ENSG00000110680 and 796, CALCA and IDBG-632774 and ENSBTAG00000047380 and 514876, Calca and IDBG-207270 and ENSMUSG00000030669 and 12310, DNA-templated and biological process this GO :0045909 and positive regulation of vasodilation and biological process this GO :0045986 and negative regulation of smooth muscle contraction and biological process this GO :0048265 and response to pain and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050965 and detection of temperature stimulus involved in sensory perception of pain and biological process this GO :0051480 and cytosolic calcium ion homeostasis and biological process this GO :0051482 and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :1990090 and cellular response to nerve growth factor stimulus and biological process, identical protein binding, nuclei, this GO :0001935 and endothelial cell proliferation and biological process this GO :0001944 and vasculature development and biological process this GO :0001976 and neurological system process involved in regulation of systemic arterial blood pressure and biological process this GO :0001984 and vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure and biological process this GO :0002027 and regulation of heart rate and biological process this GO :0002031 and G-protein coupled receptor internalization and biological process this GO :0002548 and monocyte chemotaxis and biological process this GO :0005102 and receptor binding and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007189 and adenylate cyclase-activating G-protein coupled receptor signaling pathway and biological process this GO :0007190 and activation of adenylate cyclase activity and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007218 and neuropeptide signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007566 and embryo implantation and biological process this GO :0007568 and aging and biological process this GO :0007631 and feeding behavior and biological process this GO :0008016 and regulation of heart contraction and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0009408 and response to heat and biological process this GO :0010523 and negative regulation of calcium ion transport into cytosol and biological process this GO :0030279 and negative regulation of ossification and biological process this GO :0030424 and axon and cellular component this GO :0030819 and positive regulation of cAMP biosynthetic process and biological process this GO :0031623 and receptor internalization and biological process this GO :0031645 and negative regulation of neurological system process and biological process this GO :0031716 and calcitonin receptor binding and molecular function this GO :0032147 and activation of protein kinase activity and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032730 and positive regulation of interleukin-1 alpha production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0042311 and vasodilation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043195 and terminal bouton and cellular component this GO :0043542 and endothelial cell migration and biological process this GO :0045087 and innate immune response and biological process this GO :0045651 and positive regulation of macrophage differentiation and biological process this GO :0045671 and negative regulation of osteoclast differentiation and biological process this GO :0045762 and positive regulation of adenylate cyclase activity and biological process this GO :0045776 and negative regulation of blood pressure and biological process this GO :0045778 and positive regulation of ossification and biological process this GO :0045779 and negative regulation of bone resorption and biological process this GO :0045892 and negative regulation of transcription, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005179 : hormone activity and also this GO :0005515 : protein binding and also this GO :0031716 : calcitonin receptor binding and also this GO :0032403 : protein complex binding and also this GO :0042802 : identical protein binding, this GO :0005179 : hormone activity, this GO :0005515 : protein binding, this GO :0031716 : calcitonin receptor binding, this GO :0032403 : protein complex binding, this GO :0042802 : identical protein binding, calcitonin-related polypeptide alpha |
| Identity: |
1437 |
| Gene: |
CALCA |
More about : CALCA |
| Long gene name: |
calcitonin related polypeptide alpha |
| Synonyms gene: |
CALC1 |
| Synonyms gene name: |
calcitonin 1 |
| Synonyms name: |
calcitonin |
| Locus: |
11p15, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X00356 M64486 |
| Entrez gene record: |
796 |
| Pubmed identfication: |
6546550 |
| RefSeq identity: |
NM_001741 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000159731 |
| Locus Specific Databases: |
LRG_13 |