| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
P38 MAPK |
| Specificity: |
This antibody reacts specifically with P38 MAPK |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human P38MAPK |
| Gene ID: |
1432 |
| Swiss Prot: |
Q16539 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, Jul 2008], MAP kinases act as an integration point for multiple biochemical signals, MEF2C, The activation requires its phosphorylation by MAP kinase kinases (MKKs), The substrates of this kinase include transcription regulator ATF2, This kinase is activated by various environmental stresses and proinflammatory cytokines, [provided by RefSeq, and MAX, and are involved in a wide variety of cellular processes such as proliferation, and tumor suppressor p53, as well as in genotoxic stress response, cell cycle regulator CDC25B, differentiation, or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase, transcription regulation and development, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, The protein encoded by this gene is a member of the MAP kinase family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
p38 Aha1 hAha1 |
| Also known as: |
P38 MAPK Polyclonal Antibody |
| Other name: |
Anti-P38 MAPK Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
P38 MAPK |
| Short name: |
Anti-P38 MAPK (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-P38 MAPK (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1189 |
| Gene: |
AHSA1 |
More about : AHSA1 |
| Long gene name: |
activator of HSP90 ATPase activity 1 |
| Synonyms gene: |
C14orf3 |
| Synonyms gene name: |
activator of heat shock 90kDa protein ATPase homolog 1 (yeast) , chromosome 14 open reading frame 3 AHA1 |
| Locus: |
14q24, 3 |
| Discovery year: |
1999-07-01 |
| GenBank acession: |
AJ243310 |
| Entrez gene record: |
10598 |
| Pubmed identfication: |
26796264 |
| RefSeq identity: |
NM_012111 |
| Havana BLAST/BLAT: |
OTTHUMG00000171539 |