| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
POT1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the POT1 antibody should be determined by the researcher |
| Intented use: |
This POT1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9NUX5 |
| Purity: |
Antigen affinity |
| Description: |
Alternatively spliced transcript variants have been described, Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression, Specifically, This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance, and abnormal chromosome segregation, catastrophic chromosome instability, regulating telomere length and protecting chromosome ends from illegitimate recombination, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene |
| Immunogen: |
Amino acids RVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLK of human POT1 were used as the immunogen for the POT1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the POT1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
POT1 |
| Short name: |
POT1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
POT1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17284 |
| Gene: |
POT1 |
More about : POT1 |
| Long gene name: |
protection of telomeres 1 |
| Synonyms gene name: |
pombe) , protection of telomeres 1 homolog (S |
| Synonyms: |
hPot1 DKFZp586D211 |
| Locus: |
7q31, 33 |
| Discovery year: |
2004-08-20 |
| GenBank acession: |
AK022580 |
| Entrez gene record: |
25913 |
| Pubmed identfication: |
11349150 12391173 |
| Classification: |
Shelterin complex |
| Havana BLAST/BLAT: |
OTTHUMG00000157194 |