| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
UHRF2 / NIRF |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the UHRF2 antibody should be determined by the researcher |
| Intented use: |
This UHRF2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q96PU4 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in multiple transcript variants some of which are non-protein coding, The encoded protein contains an NIRF_N domain, The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), This gene encodes a nuclear protein which is involved in cell-cycle regulation, This protein may also have a role in intranuclear degradation of polyglutamine aggregates, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation, and together they may play a role in tumorigenesis, E3 ubiquitin-protein ligase UHRF2 is an enzyme that in humans is encoded by the UHRF2 gene |
| Immunogen: |
Amino acids TIEDVSRKATIEELRERVWALFDVRPECQRLFYRGKQLEN of human NIRF/UHRF2 were used as the immunogen for the UHRF2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the UHRF2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
minor nuclear, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
UHRF2 / NIRF |
| Short name: |
UHRF2 Antibody / NIRF |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
UHRF2 (Antibody to) / NIRF |
| Alternative technique: |
antibodies |
| Identity: |
12557 |
| Gene: |
UHRF2 |
More about : UHRF2 |
| Long gene name: |
ubiquitin like with PHD and ring finger domains 2 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , ubiquitin-like with PHD and ring finger domains 2 |
| Synonyms: |
RNF107 NIRF URF2 MGC33463 TDRD23 |
| Synonyms name: |
Np95-like ring finger protein |
| Locus: |
9p24, 1 |
| Discovery year: |
2000-03-15 |
| GenBank acession: |
AF274049 |
| Entrez gene record: |
115426 |
| Pubmed identfication: |
12176013 |
| RefSeq identity: |
NM_152306 |
| Classification: |
PHD finger proteins Ring finger proteins Tudor domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000019521 |