| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ADRB1 |
| Specificity: |
This antibody reacts specifically with ADRB1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ADRB1 |
| Gene ID: |
153 |
| Swiss Prot: |
P08588 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling, This receptor binds epinephrine and norepinephrine with approximately equal affinity, Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
ADRB1 Polyclonal Antibody |
| Other name: |
Anti-ADRB1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ADRB1 |
| Short name: |
Anti-ADRB1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-adrenoceptor b 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ADRB1 and IDBG-90231 and ENSG00000043591 and 153, ADRB1R and B1AR and BETA1AR and RHR, Adrb1 and IDBG-179107 and ENSMUSG00000035283 and 11554, BT, norepinephrine binding, nuclei, this GO :0001996 and positive regulation of heart rate by epinephrine-norepinephrine and biological process this GO :0001997 and positive regulation of the force of heart contraction by epinephrine-norepinephrine and biological process this GO :0002024 and diet induced thermogenesis and biological process this GO :0002025 and vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure and biological process this GO :0003061 and positive regulation of the force of heart contraction by norepinephrine and biological process this GO :0003084 and positive regulation of systemic arterial blood pressure and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004939 and beta-adrenergic receptor activity and molecular function this GO :0004940 and beta1-adrenergic receptor activity and molecular function this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005088 and Ras guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005769 and early endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005980 and glycogen catabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007189 and adenylate cyclase-activating G-protein coupled receptor signaling pathway and biological process this GO :0007190 and activation of adenylate cyclase activity and biological process this GO :0007266 and Rho protein signal transduction and biological process this GO :0007568 and aging and biological process this GO :0007613 and memory and biological process this GO :0008144 and drug binding and molecular function this GO :0009409 and response to cold and biological process this GO :0010460 and positive regulation of heart rate and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019233 and sensory perception of pain and biological process this GO :0030165 and PDZ domain binding and molecular function this GO :0030819 and positive regulation of cAMP biosynthetic process and biological process this GO :0031649 and heat generation and biological process this GO :0031694 and alpha-2A adrenergic receptor binding and molecular function this GO :0032320 and positive regulation of Ras GTPase activity and biological process this GO :0033365 and protein localization to organelle and biological process this GO :0035240 and dopamine binding and molecular function this GO :0035811 and negative regulation of urine volume and biological process this GO :0040015 and negative regulation of multicellular organism growth and biological process this GO :0042060 and wound healing and biological process this GO :0042596 and fear response and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043950 and positive regulation of cAMP-mediated signaling and biological process this GO :0045986 and negative regulation of smooth muscle contraction and biological process this GO :0046878 and positive regulation of saliva secretion and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050873 and brown fat cell differentiation and biological process this GO :0051379 and epinephrine binding and molecular function this GO :0051380 and norepinephrine binding and molecular function this GO :0051924 and regulation of calcium ion transport and biological process this GO :0055088 and lipid homeostasis and biological process this GO :0060080 and regulation of inhibitory postsynaptic membrane potential and biological process this GO :0061051 and positive regulation of cell growth involved in cardiac muscle cell development and biological process this GO :0071880 and adenylate cyclase-activating adrenergic receptor signaling pathway and biological process this GO :0086004 and regulation of cardiac muscle cell contraction and biological process this GO :1900135 and positive regulation of renin secretion into blood stream and biological process this GO :2001259 and positive regulation of cation channel activity and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004939 : beta-adrenergic receptor activity and also this GO :0004940 : beta1-adrenergic receptor activity and also this GO :0005057 : receptor signaling protein activity and also this GO :0005088 : Ras guanyl-nucleotide exchange factor activity and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding and also this GO :0030165 : PDZ domain binding and also this GO :0031694 : alpha-2A adrenergic receptor binding and also this GO :0035240 : dopamine binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0051379 : epinephrine binding and also this GO :0051380 : norepinephrine binding, this GO :0004939 : beta-adrenergic receptor activity, this GO :0004940 : beta1-adrenergic receptor activity, this GO :0005057 : receptor signaling protein activity, this GO :0005088 : Ras guanyl-nucleotide exchange factor activity, this GO :0005515 : protein binding, this GO :0008144 : drug binding, this GO :0030165 : PDZ domain binding, this GO :0031694 : alpha-2A adrenergic receptor binding, this GO :0035240 : dopamine binding, this GO :0046982 : protein heterodimerization activity, this GO :0051379 : epinephrine binding, this GO :0051380 : norepinephrine binding, 79981 and IDBG-648826 and ENSBTAG00000001242 and 281604, adrenoceptor beta 1 |
| Identity: |
285 |
| Gene: |
ADRB1 |
More about : ADRB1 |
| Long gene name: |
adrenoceptor beta 1 |
| Synonyms gene: |
ADRB1R |
| Synonyms gene name: |
adrenergic, beta-1-, receptor |
| Locus: |
10q25, 3 |
| Discovery year: |
1990-09-10 |
| GenBank acession: |
J03019 |
| Entrez gene record: |
153 |
| Classification: |
Adrenoceptors |
| Havana BLAST/BLAT: |
OTTHUMG00000019079 |