| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
BAK |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the BAK antibody should be determined by the researcher |
| Intented use: |
This BAK antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q16611 |
| Purity: |
Antigen affinity |
| Description: |
BAK gene is localized to chromosome 6, BAK gene spans 7, By Southern blot analysis of genomic DNA from human/rodent somatic cell hybrids, It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, The BAK protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis, This protein also interacts with the tumor suppressor P53 after exposure to cell stress, This protein localizes to mitochondria, and functions to induce apoptosis, encoded by the BAK gene, is a protein that in humans, officially called Bcl2 antagonist killer, which leads to a loss in membrane potential and the release of cytochrome, 6 kb and contains 6 exons, BAK |
| Immunogen: |
Amino acids 22-211 of human BAK were used as the immunogen for the BAK antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the BAK antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
BAK |
| Short name: |
BAK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BAK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
949 |
| Gene: |
BAK1 |
More about : BAK1 |
| Long gene name: |
BCL2 antagonist/killer 1 |
| Synonyms gene: |
CDN1 |
| Synonyms gene name: |
BCL2-antagonist/killer 1 |
| Synonyms: |
BCL2L7 BAK |
| Locus: |
6p21, 31 |
| Discovery year: |
1997-10-09 |
| GenBank acession: |
U23765 |
| Entrez gene record: |
578 |
| Pubmed identfication: |
7715730 7715731 |
| RefSeq identity: |
NM_001188 |
| Classification: |
BCL2 family |
| Havana BLAST/BLAT: |
OTTHUMG00000014530 |