| Catalog number: | F42652-0.08ML |
|---|---|
| Price: | 333 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | Bak Antibody |
| Quantity: | 0.1ml |
| Other quantities: | 0.1mg 389€ 0.1ml 263€ 0.4 ml 406€ 1 tube 532€ 1 vial 470€ 1 x 1 vial 250€ |
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| Category: | Antibody |
|---|---|
| Concentration: | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: | Antigen affinity purified |
| Conjugation: | Unconjugated |
| Clone: | Polyclonal antibody |
| Recognised antigen: | Bak |
| Host animal: | Rabbit (Oryctolagus cuniculus) |
| Clonality: | Polyclonal (rabbit origin) |
| Species reactivity: | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: | ELISA, WB, IHC |
| Recommended dilutions: | IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: | Titration of the Bak antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: | This Bak antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: | Q16611 |
| Purity: | Antigen affinity |
| Description: | BAK localizes to mitochondria, BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities, It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, This protein also interacts with the tumor suppressor P53 after exposure to cell stress, and functions to induce apoptosis, which leads to a loss in membrane potential and the release of cytochrome c, BAK belongs to the BCL2 protein family |
| Immunogen: | A portion of amino acids 56-91 from the human protein was used as the immunogen for this Bak antibody |
| Storage: | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Bak antibody and store frozen at -20 deg |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: | Bak |
| Short name: | Bak Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | Bak (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 949 |
| Gene: | BAK1 | More about : BAK1 |
| Long gene name: | BCL2 antagonist/killer 1 |
| Synonyms gene: | CDN1 |
| Synonyms gene name: | BCL2-antagonist/killer 1 |
| Synonyms: | BCL2L7 BAK |
| Locus: | 6p21, 31 |
| Discovery year: | 1997-10-09 |
| GenBank acession: | U23765 |
| Entrez gene record: | 578 |
| Pubmed identfication: | 7715730 7715731 |
| RefSeq identity: | NM_001188 |
| Classification: | BCL2 family |
| Havana BLAST/BLAT: | OTTHUMG00000014530 |
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| bs-1284R-Cy5 | BAK Antibody, Cy5 Conjugated | 0.1ml | 350 € | Bioss Primary Conjugated Antibodies | human |
| bs-1284R-Cy5.5 | BAK Antibody, Cy5.5 Conjugated | 0.1ml | 350 € | Bioss Primary Conjugated Antibodies | human |
| bs-1284R-Cy7 | BAK Antibody, Cy7 Conjugated | 0.1ml | 350 € | Bioss Primary Conjugated Antibodies | human |
| bs-1284R-FITC | BAK Antibody, FITC Conjugated | 0.1ml | 333 € | Bioss Primary Conjugated Antibodies | human |