| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SGCA |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the SGCA antibody should be determined by the researcher |
| Intented use: |
This SGCA antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q16586 |
| Purity: |
Antigen affinity |
| Description: |
Its expression is thought to be restricted to striated muscle, Multiple transcript variants encoding different isoforms have been found for this gene, Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy, This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix, Alpha-sarcoglycan is a protein that in humans is encoded by the SGCA gene |
| Immunogen: |
Amino acids 24-387 of human SGCA were used as the immunogen for the SGCA antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SGCA antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SGCA |
| Short name: |
SGCA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SGCA (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10805 |
| Gene: |
SGCA |
More about : SGCA |
| Long gene name: |
sarcoglycan alpha |
| Synonyms gene: |
ADL |
| Synonyms gene name: |
alpha (50kDa dystrophin-associated glycoprotein) , sarcoglycan |
| Synonyms: |
SCARMD1 LGMD2D adhalin DMDA2 A2 |
| Synonyms name: |
50kD DAG adhalin limb girdle muscular dystrophy 2D |
| Locus: |
17q21, 33 |
| Discovery year: |
1994-12-14 |
| GenBank acession: |
L34355 |
| Entrez gene record: |
6442 |
| Pubmed identfication: |
7937874 |
| RefSeq identity: |
NM_000023 |
| Havana BLAST/BLAT: |
OTTHUMG00000162024 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_203 |