| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CACNA1C |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the CACNA1C antibody should be determined by the researcher |
| Intented use: |
This CACNA1C antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13936 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in many transcript variants encoding different proteins, CACH2, CACN2, CACNL1A1, CCHL1A1, CaV1, Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization, It is mapped to 12p13, LQT8, Some of the predicted proteins may not produce functional ion channel subunits, The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell, The calcium channel consists of a complex of alpha-1, The protein encoded by this gene binds to and is inhibited by dihydropyridine, This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel, alpha-2/delta and beta subunits in a 1:1:1 ratio, 2, 3, CACNA1C is also known as TS |
| Immunogen: |
Amino acids 1933-2026 of human CACNA1C were used as the immunogen for the CACNA1C antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CACNA1C antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CACNA1C |
| Short name: |
CACNA1C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CACNA1C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1390 |
| Gene: |
CACNA1C |
More about : CACNA1C |
| Long gene name: |
calcium voltage-gated channel subunit alpha1 C |
| Synonyms gene: |
CCHL1A1 CACNL1A1 |
| Synonyms gene name: |
L type, alpha 1C subunit , calcium channel, voltage-dependent |
| Synonyms: |
Cav1, 2 CACH2 CACN2 TS LQT8 |
| Locus: |
12p13, 33 |
| Discovery year: |
1991-01-30 |
| GenBank acession: |
AF070589 |
| Entrez gene record: |
775 |
| Pubmed identfication: |
1650913 16382099 |
| RefSeq identity: |
NM_000719 |
| Classification: |
Calcium voltage-gated channel subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000150243 |
| Locus Specific Databases: |
Gene Connection for the Heart CACNA1C database at LOVD-China LRG_334 |