| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FGL2 |
| Specificity: |
This antibody reacts specifically with FGL2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from rat FGL2 |
| Gene ID: |
84586 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, It is constitutively expressed in cytotoxic T-cells, It may play a role in physiologic functions at mucosal sites, Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes, The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED), The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds, including STAT1 and IRF1, FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
pT49 T49 |
| Also known as: |
FGL2 Polyclonal Antibody |
| Other name: |
Anti-FGL2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FGL2 |
| Short name: |
Anti-FGL2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FGL2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3696 |
| Gene: |
FGL2 |
More about : FGL2 |
| Long gene name: |
fibrinogen like 2 |
| Synonyms gene name: |
fibrinogen-like 2 |
| Locus: |
7q11, 23 |
| Discovery year: |
1999-09-07 |
| GenBank acession: |
Z36531 |
| Entrez gene record: |
10875 |
| Pubmed identfication: |
7642106 |
| RefSeq identity: |
NM_006682 |
| Classification: |
Fibrinogen C domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130681 |