| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RAB7A |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the RAB7 antibody should be determined by the researcher |
| Intented use: |
This RAB7 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P51149 |
| Purity: |
Antigen affinity |
| Description: |
Furthermore, Mutations in the lysosomal pathway result in tumor progression in melanoma cells, RAB7A functions as a key regulator in endo-lysosomal trafficking, RAB7A is involved in regulation of some specialized endosomal membrane trafficking, and endosome-lysosome transport through different protein-protein interaction cascades, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positions, such as maturation of melanosomes through modulation of SOX10 and the oncogene MYC, Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene |
| Immunogen: |
Amino acids KEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKND of human RAB7A were used as the immunogen for the RAB7 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RAB7 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RAB7A |
| Short name: |
RAB7A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member RAS oncogene family (Antibody to), RAB7A |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, PRO2706 and RAB7, RAB7A and IDBG-55277 and ENSG00000075785 and 7879, Rab7 and IDBG-253533 and ENSMUSG00000079477 and 19349, Rac GTPase binding, member RAS oncogene family, nuclei, this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005770 and late endosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006622 and protein targeting to lysosome and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0006897 and endocytosis and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007174 and epidermal growth factor catabolic process and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0008219 and cell death and biological process this GO :0008333 and endosome to lysosome transport and biological process this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component this GO :0019003 and GDP binding and molecular function this GO :0019886 and antigen processing and presentation of exogenous peptide antigen via MHC class II and biological process this GO :0030670 and pha this GO cytic vesicle membrane and cellular component this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0042470 and melanosome and cellular component this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0045022 and early endosome to late endosome transport and biological process this GO :0045335 and pha this GO cytic vesicle and cellular component this GO :0045453 and bone resorption and biological process this GO :0048365 and Rac GTPase binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0090382 and pha this GO some maturation and biological process this GO :0090383 and pha this GO some acidification and biological process this GO :0090385 and pha this GO some-lysosome fusion and biological process this GO :0097208 and alveolar lamellar body and cellular component, this GO :0003924 : GTPase activity, this GO :0003924 : GTPase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005525 : GTP binding and also this GO :0019003 : GDP binding and also this GO :0048365 : Rac GTPase binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005525 : GTP binding, this GO :0019003 : GDP binding, this GO :0048365 : Rac GTPase binding, 41314 and IDBG-646498 and ENSBTAG00000010193 and 509970, RAB7A |
| Identity: |
9788 |
| Gene: |
RAB7A |
More about : RAB7A |
| Long gene name: |
RAB7A, member RAS oncogene family |
| Synonyms gene: |
RAB7 |
| Synonyms gene name: |
RAB7, member RAS oncogene family |
| Locus: |
3q21, 3 |
| Discovery year: |
1999-03-24 |
| GenBank acession: |
X93499 |
| Entrez gene record: |
7879 |
| Pubmed identfication: |
9126495 9428630 |
| Classification: |
RAB, member RAS oncogene GTPases |
| Havana BLAST/BLAT: |
OTTHUMG00000159812 |
| Locus Specific Databases: |
LRG_266 |