| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RIP140 / NRIP1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the RIP140 antibody should be determined by the researcher |
| Intented use: |
This RIP140 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P48552 |
| Purity: |
Antigen affinity |
| Description: |
A major role for RIP140 in adipose tissue is to block the expression of genes involved in energy dissipation and mitochondrial uncoupling, Also known as RIP140, It is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors, RIP140 has an important role in regulating lipid and glucose metabolism, also known as receptor-interacting protein 140 (RIP140), and liver, and regulates gene expression in metabolic tissues including heart, including the estrogen receptor, including uncoupling protein 1 and carnitine palmitoyltransferase 1b, is a protein that in humans is encoded by the NRIP1 gene, skeletal muscle, this protein is a key regulator which modulates transcriptional activity of a variety of transcription factors, Nuclear receptor-interacting protein 1 (NRIP1) |
| Immunogen: |
Amino acids EAHLQQYSREHALKTQNANQAASERLAAMARLQE of human RIP140/NRIP1 were used as the immunogen for the RIP140 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RIP140 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RIP140 / NRIP1 |
| Short name: |
RIP140 Antibody / NRIP1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RIP140 (Antibody to) / NRIP1 |
| Alternative technique: |
antibodies |
| Identity: |
8001 |
| Gene: |
NRIP1 |
More about : NRIP1 |
| Long gene name: |
nuclear receptor interacting protein 1 |
| Synonyms: |
RIP140 |
| Synonyms name: |
receptor interacting protein 140 nuclear factor RIP140 |
| Locus: |
21q11, 1 , 2-q21 |
| Discovery year: |
1998-12-18 |
| GenBank acession: |
X84373 |
| Entrez gene record: |
8204 |
| Pubmed identfication: |
7641693 9521594 |
| RefSeq identity: |
NM_003489 |
| Havana BLAST/BLAT: |
OTTHUMG00000074323 |