| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Mouse (Mus musculus) |
| Target Protein/Peptide: |
Aromatase |
| Specificity: |
This antibody reacts specifically with Aromatase |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Aromatase |
| Gene ID: |
1588 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rabbit, Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is highly conserved amongst mammals, Many environmental chemicals may influence aromatase activity and thereby disrupt endocrine function, and is highly expressed in placental tissue, fertility and carcinogenesis, oestrogen biosynthesis, Aromatase is a key enzyme in steroidogenesis and plays an important role in sexual differentiation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ARO P-450AROM CPV1 ARO1 CYAR aromatase |
| Also known as: |
Aromatase Polyclonal Antibody |
| Other name: |
Anti-Aromatase Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Aromatase |
| Short name: |
Anti-Aromatase (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Aromatase (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2594 |
| Gene: |
CYP19A1 |
More about : CYP19A1 |
| Long gene name: |
cytochrome P450 family 19 subfamily A member 1 |
| Synonyms gene: |
CYP19 |
| Synonyms gene name: |
cytochrome P450, family 19, polypeptide 1 , subfamily A, subfamily XIX (aromatization of androgens) cytochrome P450 |
| Locus: |
15q21, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
D14473 |
| Entrez gene record: |
1588 |
| Pubmed identfication: |
8477708 |
| Classification: |
Cytochrome P450 family 19 |
| Havana BLAST/BLAT: |
OTTHUMG00000131747 |
| Locus Specific Databases: |
Human Cytochrome P450 (CYP) Allele Nomenclature Committee |