| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CD153 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
5-1ug/ml, IHC (Paraffin): 0 |
| Notes: |
Optimal dilution of the CD153 antibody should be determined by the researcher |
| Intented use: |
This CD153 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P32971 |
| Purity: |
Antigen affinity |
| Description: |
The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch, The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas, The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family, This cytokine is a ligand for TNFRSF8/CD30, This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, Two transcript variants encoding different isoforms have been found for this gene, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies, while to induce cell death and reduce cell proliferation of other lymphoma cell lines, CD153 is a ligand for CD30 |
| Immunogen: |
Amino acids 63-234 of human CD153 were used as the immunogen for the CD153 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CD153 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
membrane, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CD153 |
| Short name: |
CD153 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD153 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11938 |
| Gene: |
TNFSF8 |
More about : TNFSF8 |
| Long gene name: |
tumor necrosis factor superfamily member 8 |
| Synonyms gene: |
CD30LG |
| Synonyms gene name: |
member 8 , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
CD153 |
| Locus: |
9q32-q33, 1 |
| Discovery year: |
1993-11-08 |
| GenBank acession: |
L09753 |
| Entrez gene record: |
944 |
| Pubmed identfication: |
8391931 9349718 |
| Classification: |
Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000021025 |