| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ADM R |
| Specificity: |
This antibody reacts specifically with ADM R |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse ADM R |
| Gene ID: |
11318 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus), Mouse (Mus musculus) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function, Adrenomedullin receptor L1 expression has been reported in adrenal gland, and thyroid, bone marrow, brain, heart, kidney, liver, lung, lymph node, pancreas, skeletal muscle, small intestine, spleen, stomach, testis, Adrenomedullin Receptor L1 is a transmembrane protein that belongs to the G protein coupled receptor 1 family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AM |
| Also known as: |
ADM R Polyclonal Antibody |
| Other name: |
Anti-ADM R Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ADM R |
| Short name: |
Anti-ADM R (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-adrenomedullin R (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ADM and IDBG-31636 and ENSG00000148926 and 133, ADM and IDBG-633364 and ENSBTAG00000021048 and 280713, AM and PAMP, Adm and IDBG-206620 and ENSMUSG00000030790 and 11535, Extracellular, adrenomedullin receptor binding, this GO :0001570 and vasculogenesis and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001843 and neural tube closure and biological process this GO :0002026 and regulation of the force of heart contraction and biological process this GO :0002031 and G-protein coupled receptor internalization and biological process this GO :0005102 and receptor binding and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006171 and cAMP biosynthetic process and biological process this GO :0006701 and progesterone biosynthetic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007507 and heart development and biological process this GO :0007565 and female pregnancy and biological process this GO :0007568 and aging and biological process this GO :0008015 and blood circulation and biological process this GO :0008209 and androgen metabolic process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009409 and response to cold and biological process this GO :0009611 and response to wounding and biological process this GO :0010033 and response to organic substance and biological process this GO :0010460 and positive regulation of heart rate and biological process this GO :0019933 and cAMP-mediated signaling and biological process this GO :0030819 and positive regulation of cAMP biosynthetic process and biological process this GO :0031100 and organ regeneration and biological process this GO :0031102 and neuron projection regeneration and biological process this GO :0031623 and receptor internalization and biological process this GO :0031700 and adrenomedullin receptor binding and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032868 and response to insulin and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042594 and response to starvation and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043116 and negative regulation of vascular permeability and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045906 and negative regulation of vasoconstriction and biological process this GO :0045909 and positive regulation of vasodilation and biological process this GO :0046879 and hormone secretion and biological process this GO :0048589 and developmental growth and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0055074 and calcium ion homeostasis and biological process this GO :0060670 and branching involved in labyrinthine layer morphogenesis and biological process this GO :0060712 and spongiotrophoblast layer development and biological process this GO :0097084 and vascular smooth muscle cell development and biological process this GO :2001214 and positive regulation of vasculogenesis and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005179 : hormone activity and also this GO :0005515 : protein binding and also this GO :0031700 : adrenomedullin receptor binding, this GO :0005179 : hormone activity, this GO :0005515 : protein binding, this GO :0031700 : adrenomedullin receptor binding, adrenomedullin |
| Identity: |
259 |
| Gene: |
ADM |
More about : ADM |
| Long gene name: |
adrenomedullin |
| Locus: |
11p15, 4 |
| Discovery year: |
1994-12-15 |
| GenBank acession: |
D14874 |
| Entrez gene record: |
133 |
| Pubmed identfication: |
7688224 |
| RefSeq identity: |
NM_001124 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000165907 |