| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ADNP |
| Specificity: |
This antibody reacts specifically with ADNP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ADNP |
| Gene ID: |
23394 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ADNP is implicated in maintaining cell survival, ADNP mRNA is abundantly expressed in distinct normal tissues, The encoded protein contains one homeobox and nine zinc finger domains, and colon cancers, and high expression levels were encountered in malignant cells, bladder, including breast, ovarian, pancreatic, perhaps through modulation of p53, suggesting that it functions as a transcription factor, The activity dependent neuroprotective protein (ADNP) gene is frequently amplified in many neoplasias |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0784 ADNP1 |
| Also known as: |
ADNP Polyclonal Antibody |
| Other name: |
Anti-ADNP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ADNP |
| Short name: |
Anti-ADNP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-activity-dependent neuroprotector homeobox (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ADNP and IDBG-643241 and ENSBTAG00000000340 and 533757, ADNP and IDBG-81086 and ENSG00000101126 and 23394, ADNP1 and MRD28, Adnp and IDBG-213108 and ENSMUSG00000051149 and 11538, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0046872 and metal ion binding and molecular function, metal ion binding, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046872 : metal ion binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046872 : metal ion binding, activity-dependent neuroprotector homeobox |
| Identity: |
15766 |
| Gene: |
ADNP |
More about : ADNP |
| Long gene name: |
activity dependent neuroprotector homeobox |
| Synonyms gene name: |
activity-dependent neuroprotector |
| Synonyms name: |
ADNP homeobox 1 |
| Locus: |
20q13, 13 |
| Discovery year: |
2001-05-31 |
| GenBank acession: |
AF250860 |
| Entrez gene record: |
23394 |
| Pubmed identfication: |
9872452 11013255 |
| RefSeq identity: |
NM_181442 |
| Classification: |
ZF class homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000032737 |