| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Filaggrin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the Filaggrin antibody should be determined by the researcher |
| Intented use: |
This Filaggrin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P20930 |
| Purity: |
Antigen affinity |
| Description: |
It is initially synthesized as a polyprotein precursor, Mutations in this gene are associated with ichthyosis vulgaris, The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis, and is subsequently proteolytically processed into individual functional filaggrin molecules, profilaggrin (consisting of multiple filaggrin units of 324 aa each), profillagrin is encoded by the FLG gene, which is localized in keratohyalin granules, which is part of the S100 fused-type protein (SFTP) family within the epidermal differentiation complex on chromosome 1q21, In humans |
| Immunogen: |
Amino acids 1-261 of human Filaggrin were used as the immunogen for the Filaggrin antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Filaggrin antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Filaggrin |
| Short name: |
Filaggrin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Filaggrin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3748 |
| Gene: |
FLG |
More about : FLG |
| Long gene name: |
filaggrin |
| Locus: |
1q21, 3 |
| Discovery year: |
1989-10-18 |
| GenBank acession: |
XM_048104 |
| Entrez gene record: |
2312 |
| Pubmed identfication: |
2740331 2248957 16444271 |
| RefSeq identity: |
NM_002016 |
| Classification: |
S100 fused type protein family EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000012202 |
| Locus Specific Databases: |
LRG_1028 |