| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Cyclin A2 / CCNA2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the Cyclin A2 antibody should be determined by the researcher |
| Intented use: |
This Cyclin A2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P20248 |
| Purity: |
Antigen affinity |
| Description: |
And Cyclin A2 is synthesized at the onset of S phase and localizes to the nucleus, Cyclins function as regulators of CDK kinases, Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event, In contrast to cyclin A1, Phosphorylation of CDC6 and MCM4 by the cyclin A2-CDK2 complex prevents re-replication of DNA during the cell cycle, The protein encoded by this gene belongs to the highly conserved cyclin family, This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions, is mapped to 4q27, known as CCNA2, this cyclin is expressed in all tissues tested, where the cyclin A2-CDK2 complex is implicated in the initiation and progression of DNA synthesis, which is present only in germ cells, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle, Cyclin A2 |
| Immunogen: |
Amino acids 10-168 of human Cyclin A2 were used as the immunogen for the Cyclin A2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cyclin A2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Cyclin A2 / CCNA2 |
| Short name: |
Cyclin A2 Antibody / CCNA2 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cyclin A2 (Antibody to) / CCNA2 |
| Alternative technique: |
antibodies |
| Identity: |
1578 |
| Gene: |
CCNA2 |
More about : CCNA2 |
| Long gene name: |
cyclin A2 |
| Synonyms gene: |
CCNA CCN1 |
| Locus: |
4q27 |
| Discovery year: |
1990-04-09 |
| Entrez gene record: |
890 |
| Pubmed identfication: |
1675006 |
| RefSeq identity: |
NM_001237 |
| Classification: |
Cyclins |
| Havana BLAST/BLAT: |
OTTHUMG00000133072 |