| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PTPN2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the PTPN2 antibody should be determined by the researcher |
| Intented use: |
This PTPN2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P17706 |
| Purity: |
Antigen affinity |
| Description: |
Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, Members of the PTP family share a highly conserved catalytic motif, Multiple alternatively spliced transcript variants encoding different isoforms have been found, PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family, Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, and oncogenic transformation, differentiation, have been reported, mitotic cycle, respectively, which is essential for the catalytic activity, which suggested the roles in growth factor mediated cell signaling, TCPTP is also called as PTPN2 |
| Immunogen: |
Amino acids 1-330 of human PTPN2 were used as the immunogen for the PTPN2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PTPN2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Nuclear |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PTPN2 |
| Short name: |
PTPN2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PTPN2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9650 |
| Gene: |
PTPN2 |
More about : PTPN2 |
| Long gene name: |
non-receptor type 2 , protein tyrosine phosphatase |
| Synonyms gene: |
PTPT |
| Synonyms: |
TCELLPTP TC-PTP TCPTP |
| Locus: |
18p11, 21 |
| Discovery year: |
1991-09-13 |
| GenBank acession: |
M25393 |
| Entrez gene record: |
5771 |
| Pubmed identfication: |
2164224 |
| RefSeq identity: |
NM_002828 NM_080422 NM_080423 |
| Classification: |
Protein tyrosine phosphatases, non-receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000131702 |