| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
HSC70 / HSPA8 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the HSC70 antibody should be determined by the researcher |
| Intented use: |
This HSC70 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P11142 |
| Purity: |
Antigen affinity |
| Description: |
And the HSPA8 gene is mapped on 11q24, FORMERLY, HSC71, HSP73, HSP73 also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell, HSPA10, HSPA8 plays an important role in cells by transiently associating with nascent polypeptides to facilitate correct folding, Hsc70 formed a complex with Hsp40 and Hip, In the absence of Il3, LAP1 or LPS-ASSOCIATED PROTEIN 1, Rapid decay involves AU-rich binding protein AUF1, The HSPA8 gene contains 9 exons and spans 5 kb, The deduced HSPA8 protein has 646 amino acids and a predicted molecular mass of 70, and poly (A)-binding protein, and this complex, formed a high-stability complex with Bim mRNA that protected it from ribonucleases, in association with Eif4g and Pabp, is a heat shock protein that in humans is encoded by the HSPA8 gene, translation initiation factor EIF4G, which complexes with heat-shock proteins HSC70 and HSP70, 1, 899 Da, HSPA8 (heat shock 70kDa protein 8) also known as HSC70 |
| Immunogen: |
Amino acids 520-614 of human HSPA8/HSC70 were used as the immunogen for the HSC70 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HSC70 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
HSC70 / HSPA8 |
| Short name: |
HSC70 Antibody / HSPA8 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HSC70 (Antibody to) / HSPA8 |
| Alternative technique: |
antibodies |
| Identity: |
5241 |
| Gene: |
HSPA8 |
More about : HSPA8 |
| Long gene name: |
heat shock protein family A (Hsp70) member 8 |
| Synonyms gene: |
HSPA10 |
| Synonyms gene name: |
heat shock 70kD protein 8 heat shock 70kDa protein 8 |
| Synonyms: |
HSC71 HSC70 HSP73 |
| Locus: |
11q24, 1 |
| Discovery year: |
1995-05-08 |
| GenBank acession: |
Y00371 |
| Entrez gene record: |
3312 |
| Pubmed identfication: |
8530083 3037489 |
| Classification: |
NineTeen complex Heat shock 70kDa proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000166030 |