| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TTR / Transthyretin / Prealbumin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the Transthyretin antibody should be determined by the researcher |
| Intented use: |
This Transthyretin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P02766 |
| Purity: |
Antigen affinity |
| Description: |
Due to increased stability of the tetramer form of this encoded protein in mouse, In humans, It is mapped to chromosome region 18q11, The protein consists of a tetramer of identical subunits, This gene encodes a carrier protein responsible for the transport of thyroid hormones and retinol, compared to the human protein, this gene product has a reduced tendency to form amyloid fibrils, this protein binds beta-amyloid preventing its aggregation and providing a neuroprotective role in Alzheimer's disease, 1, 2-q12, Transthyretin (TTR) is also known as prealbumin |
| Immunogen: |
Amino acids 21-147 of human TTR were used as the immunogen for the Transthyretin antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Transthyretin antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
membrane, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TTR / Transthyretin / Prealbumin |
| Short name: |
TTR Antibody / Transthyretin / Prealbumin |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TTR (Antibody to) / Transthyretin / Prealbumin |
| Alternative technique: |
antibodies |
| Identity: |
12405 |
| Gene: |
TTR |
More about : TTR |
| Long gene name: |
transthyretin |
| Synonyms gene: |
PALB CTS1 |
| Synonyms gene name: |
amyloidosis type I carpal tunnel syndrome 1 , prealbumin |
| Synonyms: |
HsT2651 CTS |
| Locus: |
18q12, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M10605 |
| Entrez gene record: |
7276 |
| Pubmed identfication: |
8309582 |
| RefSeq identity: |
NM_000371 |
| Classification: |
Gla domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000131984 |
| Locus Specific Databases: |
LSDB list LRG_416 |