| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SNAIL / SNAI1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the SNAIL antibody should be determined by the researcher |
| Intented use: |
This SNAIL antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O95863 |
| Purity: |
Antigen affinity |
| Description: |
And it is located in 16q24, At least two variants of a similar processed pseudogene have been found on chromosome 2, It is studied that SNAIL gene may show a role in recurrence of breast cancer by downregulating E-cadherin and inducing anepithelial to mesenchymal transition, The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo, commonly known as Snail, is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm, 3, The Drosophila embryonic protein SNAI1 |
| Immunogen: |
Amino acids AAFPGLGQVPKQLAQLSEAKDLQARKAFN of human SNAIL were used as the immunogen for the SNAIL antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SNAIL antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SNAIL / SNAI1 |
| Short name: |
SNAIL Antibody / SNAI1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SNAIL (Antibody to) / snail homolog 1 (Drosophila) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function this GO :0060021 and palate development and biological process this GO :0060536 and cartilage morphogenesis and biological process this GO :0060707 and trophoblast giant cell differentiation and biological process this GO :0060806 and negative regulation of cell differentiation involved in embryonic placenta development and biological process this GO :0060972 and left/right pattern formation and biological process this GO :0061314 and Notch signaling involved in heart development and biological process this GO :1902230 and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :2000810 and regulation of tight junction assembly and biological process, SNAI1 and IDBG-80676 and ENSG00000124216 and 6615, Snai1 and IDBG-213071 and ENSMUSG00000042821 and 20613, dJ710H13, metal ion binding, nuclei, signal transduction by p53 class mediator and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045892 and negative regulation of transcription, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001227 and RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001649 and osteoblast differentiation and biological process this GO :0001707 and mesoderm formation and biological process this GO :0001837 and epithelial to mesenchymal transition and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007498 and mesoderm development and biological process this GO :0010718 and positive regulation of epithelial to mesenchymal transition and biological process this GO :0010957 and negative regulation of vitamin D biosynthetic process and biological process this GO :0016477 and cell migration and biological process this GO :0019900 and kinase binding and molecular function this GO :0030335 and positive regulation of cell migration and biological process this GO :0031069 and hair follicle morphogenesis and biological process this GO :0043518 and negative regulation of DNA damage response, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0001227 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0005515 : protein binding and also this GO :0019900 : kinase binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046872 : metal ion binding, this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0001227 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0005515 : protein binding, this GO :0019900 : kinase binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046872 : metal ion binding, 1 and SLUGH2 and SNA and SNAH and SNAIL and SNAIL1, 61987 and IDBG-643208 and ENSBTAG00000014554 and 504492, snail homolog 1 (Drosophila) |
| Identity: |
11128 |
| Gene: |
SNAI1 |
More about : SNAI1 |
| Long gene name: |
snail family transcriptional repressor 1 |
| Synonyms gene name: |
snail 1 (drosophila homolog), zinc finger protein snail homolog 1 (Drosophila) snail family zinc finger 1 |
| Synonyms: |
SNA SLUGH2 SNAH SNAIL1 SNAIL |
| Locus: |
20q13, 13 |
| Discovery year: |
1998-07-03 |
| GenBank acession: |
AF125377 |
| Entrez gene record: |
6615 |
| Pubmed identfication: |
10585766 |
| Classification: |
Zinc fingers C2H2-type SNAG transcriptional repressors |
| Havana BLAST/BLAT: |
OTTHUMG00000033048 |