| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRIO / Triple functional domain protein |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the TRIO antibody should be determined by the researcher |
| Intented use: |
This TRIO antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O75962 |
| Purity: |
Antigen affinity |
| Description: |
Additionally, These domains suggest that this enzyme may play a key role in several signaling pathways that control cell proliferation, This gene encodes a large protein that functions as a GDP to GTP exchange factor, This protein promotes the reorganization of the actin cytoskeleton, respectively, specific for Rac1 and RhoA, the TRIO protein contains 3 functional domains: a serine/threonine kinase domain and 2 guanine nucleotide exchange factor (GEF) domains for the family of Rho-like GTPases, thereby playing a role in cell migration and growth, Triple functional domain protein is a protein that in humans is encoded by the TRIO gene |
| Immunogen: |
Amino acids QLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQH of human TRIO were used as the immunogen for the TRIO antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRIO antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRIO / Triple functional domain protein |
| Short name: |
TRIO Antibody / Triple functional domain protein |
| Technique: |
antibodies against human proteins, antibodies for, functional |
| Alternative name: |
trio Rho guanine nucleotide exchange factor (Antibody to) / Triple functional domain protein |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ARHGEF23 and tgat, Plasma membranes, TRIO and IDBG-12835 and ENSG00000038382 and 7204, TRIO and IDBG-631218 and ENSBTAG00000005514 and 538292, Trio and IDBG-131599 and ENSMUSG00000022263 and 223435, alcohol group as acceptor, alcohol group as acceptor and also this GO :0019899 : enzyme binding, alcohol group as acceptor and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007185 and transmembrane receptor protein tyrosine phosphatase signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0009103 and lipopolysaccharide biosynthetic process and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005089 : Rho guanyl-nucleotide exchange factor activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0016773 : phosphotransferase activity, this GO :0019899 : enzyme binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0016773 : phosphotransferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, trio Rho guanine nucleotide exchange factor |
| Identity: |
12303 |
| Gene: |
TRIO |
More about : TRIO |
| Long gene name: |
trio Rho guanine nucleotide exchange factor |
| Synonyms gene name: |
triple functional domain (PTPRF interacting) |
| Synonyms: |
ARHGEF23 |
| Locus: |
5p15, 2 |
| Discovery year: |
1997-01-29 |
| GenBank acession: |
AF091395 |
| Entrez gene record: |
7204 |
| Pubmed identfication: |
8643598 |
| RefSeq identity: |
NM_007118 |
| Classification: |
Rho guanine nucleotide exchange factors I-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000131057 |