| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PRC1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the PRC1 antibody should be determined by the researcher |
| Intented use: |
This PRC1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O43663 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in multiple transcript variants, And this protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs), It is located in the nucleus during interphase, It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly, PRC1 protein is expressed at relatively high levels during S and G2/M phases of the cell cycle before dropping dramatically after mitotic exit and entrance into G1 phase, This gene is mapped to chromosome 15q26, and localizes to the cell midbody during cytokinesis, becomes associated with the mitotic spindle in a highly dynamic manner during anaphase, 1 based on an alignment of the PRC1 sequence with the genomic sequence, Protein Regulator of cytokinesis 1 (PRC1) is a protein that in humans is encoded by the PRC1 gene and is involved in cytokinesis |
| Immunogen: |
Amino acids 1-233 of human PRC1 were used as the immunogen for the PRC1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PRC1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PRC1 |
| Short name: |
PRC1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
protein regulator on cytokinesis 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ASE1, BT, PRC1 and IDBG-30703 and ENSG00000198901 and 9055, Prc1 and IDBG-194901 and ENSMUSG00000038943 and 233406, identical protein binding, nuclei, this GO :0000022 and mitotic spindle elongation and biological process this GO :0000226 and microtubule cytoskeleton organization and biological process this GO :0000910 and cytokinesis and biological process this GO :0000922 and spindle pole and cellular component this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005819 and spindle and cellular component this GO :0005876 and spindle microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0008017 and microtubule binding and molecular function this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0042802 and identical protein binding and molecular function, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008017 : microtubule binding and also this GO :0019901 : protein kinase binding and also this GO :0042802 : identical protein binding, this GO :0008017 : microtubule binding, this GO :0019901 : protein kinase binding, this GO :0042802 : identical protein binding, 20428 and IDBG-629366 and ENSBTAG00000018643 and 767818, protein regulator of cytokinesis 1 |
| Identity: |
9341 |
| Gene: |
PRC1 |
More about : PRC1 |
| Long gene name: |
protein regulator of cytokinesis 1 |
| Synonyms: |
ASE1 |
| Synonyms name: |
anaphase spindle elongation 1 homolog (S, cerevisiae) |
| Locus: |
15q26, 1 |
| Discovery year: |
1999-07-01 |
| GenBank acession: |
AF044588 |
| Entrez gene record: |
9055 |
| Pubmed identfication: |
9885575 |
| RefSeq identity: |
NM_003981 |
| Havana BLAST/BLAT: |
OTTHUMG00000171685 |