| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ApoE |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the ApoE antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This ApoE antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
348 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in multiple ApoE transcript variants, It binds to a specific liver and peripheral cell receptor, Mutations in ApoE result in familial dysbetalipoproteinemia, The gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes, also known as AD2 or LPG, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents, in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants, is a major apoprotein of the chylomicron, or type III hyperlipoproteinemia (HLP III), Apolipoprotein E |
| Immunogen: |
Human partial recombinant protein (AA 19-317) was used as the immunogen for this ApoE antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ApoE antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ApoE |
| Short name: |
ApoE Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
apolipoprotein E (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
613 |
| Gene: |
APOE |
More about : APOE |
| Long gene name: |
apolipoprotein E |
| Synonyms gene: |
AD2 |
| Synonyms gene name: |
Alzheimer disease 2 (APOE*E4-associated, late onset) |
| Locus: |
19q13, 32 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
K00396 |
| Entrez gene record: |
348 |
| Pubmed identfication: |
10662539 |
| RefSeq identity: |
NM_000041 |
| Classification: |
Apolipoproteins |
| Havana BLAST/BLAT: |
OTTHUMG00000128901 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |