| Catalog number: | R31725 |
|---|---|
| Price: | 625 € |
| Supplier: | MBS Polyclonals_1 |
| Product name: | PER2 Antibody |
| Quantity: | 50ug |
| Other quantities: | 0.025mg 176€ 0.1mg 320€ 1 vial 521€ |
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| Category: | Antibody |
|---|---|
| Concentration: | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: | Antigen affinity purified |
| Conjugation: | Unconjugated |
| Clone: | Polyclonal antibody |
| Recognised antigen: | PER2 |
| Host animal: | Rabbit (Oryctolagus cuniculus) |
| Clonality: | Polyclonal (rabbit origin) |
| Species reactivity: | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: | WB |
| Recommended dilutions: | 5-1ug/ml, Western blot: 0 |
| Notes: | Titration of the PER2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: | This PER2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: | 8864 |
| Purity: | Antigen affinity |
| Description: | It has been showed that PER2 can positively stimulate activity of the Bmal1-Npas2 transcription complex and, It is involved in a negative-feedback loop that attenuates estrogen stimulation and links the circadian cycle to estrogen receptor signaling, Npas2 transcriptionally regulates delta-aminolevulinate synthase, The protein also functions in tumor suppression by regulating DNA damage-responsive pathways, The rhythmic levels of PER2 are critical for circadian oscillations in cells and intact organisms, in turn, the primary circadian pacemaker in the mammalian brain, Period circadian protein homolog 2 is a member of the Period family of proteins and is expressed in a circadian pattern in the suprachiasmatic nucleus |
| Immunogen: | Human partial recombinant protein (AA 13-330) was used as the immunogen for this PER2 antibody |
| Storage: | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PER2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: | PER2 |
| Short name: | PER2 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | PER2 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 8846 |
| Gene: | PER2 | More about : PER2 |
| Long gene name: | period circadian clock 2 |
| Synonyms gene name: | period (Drosophila) homolog 2 period homolog 2 (Drosophila) |
| Synonyms: | KIAA0347 |
| Locus: | 2q37, 3 |
| Discovery year: | 1999-06-11 |
| GenBank acession: | AB002345 |
| Entrez gene record: | 8864 |
| Pubmed identfication: | 9427249 17218255 |
| RefSeq identity: | NM_022817 |
| Havana BLAST/BLAT: | OTTHUMG00000152884 |
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