| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Numb |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Numb antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Numb antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
8650 |
| Purity: |
Antigen affinity |
| Description: |
Additionally, LNX1, Numb also plays a crucial role in asymmetrical cell division during development, The encoded protein, The primary function of Numb in cell differentiation is as an inhibitor of <, allowing for differential cell fate specification in the central and peripheral nervous systems, and NOTCH1, is a membrane-bound protein that has been shown to associate with EPS15, signaling which is essential for maintaining self-renewal potential in stem and progenitor cells, the protein product controls binary cell fate decisions in the peripheral and central nervous systems of both invertebrates and mammals during neurogenesis, whose degradation is induced in a proteasome-dependent manner by <, /a>, /a>, /search_result, /search_result, MDM2<, Notch<, Numb is a protein that in humans is encoded by the gene of the same name, a href=, a href=, php?search_txt=mdm>, php?search_txt=notch> |
| Immunogen: |
Amino acids 194-220 (SFRVTTATEQAEREEIMKQMQDAKKAE-human) were used as the immunogen for this Numb antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Numb antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Numb |
| Short name: |
Numb Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Numb (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8060 |
| Gene: |
NUMB |
More about : NUMB |
| Long gene name: |
NUMB, endocytic adaptor protein |
| Synonyms gene: |
C14orf41 |
| Synonyms gene name: |
numb (Drosophila) homolog chromosome 14 open reading frame 41 numb homolog (Drosophila) |
| Locus: |
14q24, 3 |
| Discovery year: |
1999-03-12 |
| GenBank acession: |
L40393 |
| Entrez gene record: |
8650 |
| Pubmed identfication: |
11121447 |
| Havana BLAST/BLAT: |
OTTHUMG00000171436 |