| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NEDD9 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the NEDD9 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This HEF1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
4739 |
| Purity: |
Antigen affinity |
| Description: |
Additionally, It has also been reported to have a role in cancer metastasis, Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways, NEDD9 is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, NEDD9 is a highly relevant cancer gene that governs metastatic potential in human melanoma, The protein encoded by this gene is a member of the CRK-associated substrates family, also called Enhancer of filamentation 1 (EF1), is a protein that in humans is encoded by the NEDD9 gene, it has been speculated that it may be an important linking element between extracellular signaling and regulation of the cytoskeleton, migration and invasion as well as apoptosis and the cell cycle, Neural cell expressed developmentally down regulated 9 |
| Immunogen: |
Human partial recombinant protein (AA 273-E21) was used as the immunogen for this NEDD9 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the NEDD9 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NEDD9 |
| Short name: |
NEDD9 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
developmentally down-regulated 9 (Antibody to), neural precursor cellular expressed |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CAS-L and CAS2 and CASL and CASS2 and HEF1, NEDD9 and IDBG-61538 and ENSG00000111859 and 4739, NEDD9 and IDBG-636135 and ENSBTAG00000006287 and, Nedd9 and IDBG-146895 and ENSMUSG00000021365 and 18003, developmentally down-regulated 9, nuclei, protein binding, this GO :0000922 and spindle pole and cellular component this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005819 and spindle and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0005938 and cell cortex and cellular component this GO :0007010 and cytoskeleton organization and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0030027 and lamellipodium and cellular component this GO :0040008 and regulation of growth and biological process this GO :0051017 and actin filament bundle assembly and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, neural precursor cell expressed |
| Identity: |
7733 |
| Gene: |
NEDD9 |
More about : NEDD9 |
| Long gene name: |
developmentally down-regulated 9 , neural precursor cell expressed |
| Synonyms: |
HEF1 CAS-L CASS2 |
| Synonyms name: |
Cas scaffolding protein family member 2 Cas-like |
| Locus: |
6p24, 2 |
| Discovery year: |
1994-01-21 |
| GenBank acession: |
L43821 |
| Entrez gene record: |
4739 |
| RefSeq identity: |
NM_006403 |
| Classification: |
Cas scaffolding proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000014255 |