| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MUC5AC Mucin-5AC |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the MUC5AC antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This MUC5AC antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
4586 |
| Purity: |
Antigen affinity |
| Description: |
It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold, It is also a direct and critical mediator of resistance during intestinal nematode infection, It is mapped to 11p15, MUC5AC is highly expressed in adult trachea and stomach, This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease(COPD), 5, Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene |
| Immunogen: |
Human partial recombinant protein (4848-5030) was used as the immunogen for this MUC5AC antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MUC5AC antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MUC5AC Mucin-5AC |
| Short name: |
MUC5AC Antibody Mucin-5AC |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
oli this GO meric mucus/electrophoretic matrix-forming (Antibody to) Mucin-5AC, mucin 5AC |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
IDBG-645651 and IDBG-645651 and ENSBTAG00000038262 and, MUC5AC and IDBG-229951 and ENSG00000215182 and 4586, Muc5ac and IDBG-212386 and ENSMUSG00000037974 and 17833, leB and MUC5 and TBM, multiple, oli this GO meric mucus/gel-forming, protein binding, this GO :0005515 and protein binding and molecular function, this GO :0005515 : protein binding, this GO :0005515 : protein binding, mucin 5AC |
| Identity: |
7515 |
| Gene: |
MUC5AC |
More about : MUC5AC |
| Long gene name: |
mucin 5AC, oligomeric mucus/gel-forming |
| Synonyms gene name: |
mucin 5, subtypes A and C, tracheobronchial/gastric |
| Synonyms: |
MUC5 |
| Locus: |
11p15, 5 |
| Discovery year: |
1995-04-05 |
| GenBank acession: |
AJ001402 AJ298317 |
| Entrez gene record: |
4586 |
| Pubmed identfication: |
7826332 9588204 |
| RefSeq identity: |
XM_001130382 |
| Classification: |
Mucins |
| Havana BLAST/BLAT: |
OTTHUMG00000154270 |