| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MFN1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the MFN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This MFN1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
55669 |
| Purity: |
Antigen affinity |
| Description: |
It has two key domains, It is a mitochondrial member of the dynamin family of molecules, It is ubiquitously expressed, MFN1 is known to form oligomers, One is a coiled, Overexpression causes perinuclear mitochondrial clustering, The protein encoded by this gene is a mediator of mitochondrial fusion, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion, and found in the outer mitochondrial membrane, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology, and to undergo ubiquitination by MARCH5, either with itself or MFN, 1/2 binding, 2, Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene, coil region that mediates MFN |
| Immunogen: |
An amino acid sequence from the N-terminal of human Mitofusin 1 (DQLLEFVTEGSHFVEATYKNPELDRIA) was used as the immunogen for this MFN1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MFN1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MFN1 |
| Short name: |
MFN1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MFN1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18262 |
| Gene: |
MFN1 |
More about : MFN1 |
| Long gene name: |
mitofusin 1 |
| Synonyms: |
FLJ20693 |
| Locus: |
3q26, 33 |
| Discovery year: |
2003-02-25 |
| GenBank acession: |
AF054986 |
| Entrez gene record: |
55669 |
| Pubmed identfication: |
8358434 11181170 |
| RefSeq identity: |
NM_017927 |
| Havana BLAST/BLAT: |
OTTHUMG00000157385 |