| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
JAG2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the JAG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This JAG2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
3714 |
| Purity: |
Antigen affinity |
| Description: |
It is mapped to 14q32, Jagged 2 can promote the growth and dissemination of uveal melanoma cells, Notch ligands Delta1 and JAG2 are subject to presenilin-dependent, The protein encoded by this gene is one of several ligands that activate<, also known as SER2, intramembranous gamma-secretase processing, is a protein that in humans is encoded by the JAG2 gene, resulting in the production of soluble intracellular derivatives, /a>, /search_result, 33, Jagged 2, Notch<, a href=, and related receptors, php?search_txt=notch> |
| Immunogen: |
Human partial recombinant protein (AA 962-1238) was used as the immunogen for this JAG2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the JAG2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
JAG2 |
| Short name: |
JAG2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
jagged 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
HJ2 and SER2, JAG2 and IDBG-23019 and ENSG00000184916 and 3714, JAG2 and IDBG-635883 and ENSBTAG00000007319 and 517405, Jag2 and IDBG-175254 and ENSMUSG00000002799 and 16450, Plasma membranes, growth factor activity, this GO :0001501 and skeletal system development and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0003016 and respiratory system process and biological process this GO :0005112 and Notch binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007049 and cell cycle and biological process this GO :0007154 and cell communication and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007220 and Notch receptor processing and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008083 and growth factor activity and molecular function this GO :0009912 and auditory receptor cell fate commitment and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016331 and morphogenesis of embryonic epithelium and biological process this GO :0030154 and cell differentiation and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030217 and T cell differentiation and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042492 and gamma-delta T cell differentiation and biological process this GO :0045061 and thymic T cell selection and biological process this GO :1990134 and epithelial cell apoptotic process involved in palatal shelf morphogenesis and biological process, this GO :0005112 : Notch binding, this GO :0005112 : Notch binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, jagged 2 |
| Identity: |
6189 |
| Gene: |
JAG2 |
More about : JAG2 |
| Long gene name: |
jagged 2 |
| Locus: |
14q32, 33 |
| Discovery year: |
1998-06-05 |
| GenBank acession: |
AF020201 |
| Entrez gene record: |
3714 |
| Pubmed identfication: |
9315665 10662552 |
| Havana BLAST/BLAT: |
OTTHUMG00000140172 |