| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
HIF-1-alpha |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the HIF-1-alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This HIF-1-alpha antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
3091 |
| Purity: |
Antigen affinity |
| Description: |
It is crucial for the cellular response to hypoxia and plays a pivotal role in cellular adaptation to changes in oxygen availability, erythropoiesis and glycolysis, including angiogenesis, Hypoxia-inducible factor 1a (HIF-1-alpha) is a transcription factor that mediates cellular and systemic homeostatic responses to reduced O2 availability in mammals |
| Immunogen: |
Amino acids 703-732 (EEELNPKILALQNAQRKRKMEHDGSLFQAV-human) were used as the immunogen for this HIF-1-alpha antibody |
| Storage: |
After reconstitution, Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, The lyophilized HIF-1-alpha antibody can be stored at 4oC |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
HIF-1-alpha |
| Short name: |
HIF-1-alpha Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HIF-1-a (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18420 |
| Gene: |
SETD2 |
More about : SETD2 |
| Long gene name: |
SET domain containing 2 |
| Synonyms: |
HYPB HIF-1 KIAA1732 FLJ23184 KMT3A |
| Locus: |
3p21, 31 |
| Discovery year: |
2006-02-15 |
| GenBank acession: |
AJ238403 |
| Entrez gene record: |
29072 |
| Pubmed identfication: |
16118227 11461154 |
| RefSeq identity: |
NM_014159 |
| Classification: |
Lysine methyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000133514 |
| Locus Specific Databases: |
LRG_775 |