| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MCAK |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the MCAK antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This MCAK antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
11004 |
| Purity: |
Antigen affinity |
| Description: |
It is mapped to 1p34, MCAK uses microtubule depolymerizing activity to correct improper microtubule attachments at kinetochores, Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division, The protein encoded by this gene is a member of kinesin-like protein family, This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation, also called Mitotic centromere associated kinesin (MCAK), is a protein that in humans is encoded by the KIF2C gene, 1, Kinesin-like protein |
| Immunogen: |
Human partial recombinant protein (AA 531-725) was used as the immunogen for this MCAK antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MCAK antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MCAK |
| Short name: |
MCAK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MCAK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6393 |
| Gene: |
KIF2C |
More about : KIF2C |
| Long gene name: |
kinesin family member 2C |
| Synonyms gene: |
KNSL6 |
| Synonyms gene name: |
kinesin-like 6 (mitotic centromere-associated kinesin) |
| Synonyms: |
MCAK CT139 |
| Locus: |
1p34, 1 |
| Discovery year: |
1999-09-07 |
| GenBank acession: |
U63743 |
| Entrez gene record: |
11004 |
| Pubmed identfication: |
9434124 |
| RefSeq identity: |
NM_006845 |
| Classification: |
Kinesins |
| Havana BLAST/BLAT: |
OTTHUMG00000008416 |