| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IRF4 (MUM1) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the IRF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This IRF4 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
3662 |
| Purity: |
Antigen affinity |
| Description: |
Additionally, IL17 -producing Th17 cells, IRF4 inhibition is toxic to myeloma cell lines, IRF4 is a transcription factor, IRF4 is a transcription factor that has been implicated in acute leukemia, In melanocytic cells, It is located on 6p25, This gene is strongly associated with pigmentation, also known as MUM1, and IL9 -producing Th9 cells, and brown hair color, and it is essential for the development of T helper-2 (Th2) cells, blue eyes, freckles, is a protein that in humans is encoded by the IRF4 gene, regardless of transforming oncogenic mechanism, sensitivity of skin to sun exposure, the gene may be regulated by MITF, 3, Interferon regulatory factor 4 |
| Immunogen: |
Human partial recombinant protein (AA 272-451) was used as the immunogen for this IRF4 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IRF4 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IRF4 (MUM1) |
| Short name: |
IRF4 Antibody (MUM1) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
interferon regulatory factor 4 (Antibody to) (MUM1) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006479 and protein methylation and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0016020 and membrane and cellular component this GO :0016279 and protein-lysine N-methyltransferase activity and molecular function this GO :0018022 and peptidyl-lysine methylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0034122 and negative regulation of toll-like receptor signaling pathway and biological process this GO :0042110 and T cell activation and biological process this GO :0042832 and defense response to protozoan and biological process this GO :0043011 and myeloid dendritic cell differentiation and biological process this GO :0043388 and positive regulation of DNA binding and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043966 and histone H3 acetylation and biological process this GO :0043967 and histone H4 acetylation and biological process this GO :0045082 and positive regulation of interleukin-10 biosynthetic process and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045368 and positive regulation of interleukin-13 biosynthetic process and biological process this GO :0045404 and positive regulation of interleukin-4 biosynthetic process and biological process this GO :0045622 and regulation of T-helper cell differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0072540 and T-helper 17 cell lineage commitment and biological process, IRF4 and IDBG-55681 and ENSG00000137265 and 3662, IRF4 and IDBG-636960 and ENSBTAG00000002929 and 506141, Irf4 and IDBG-141793 and ENSMUSG00000021356 and 16364, LSIRF and MUM1 and NF-EM5, nuclei, sequence-specific DNA binding, this GO :0000788 and nuclear nucleosome and cellular component this GO :0000975 and regulatory region DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000975 : regulatory region DNA binding, this GO :0000975 : regulatory region DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0016279 : protein-lysine N-methyltransferase activity and also this GO :0043565 : sequence-specific DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0016279 : protein-lysine N-methyltransferase activity, this GO :0043565 : sequence-specific DNA binding, interferon regulatory factor 4 |
| Identity: |
6119 |
| Gene: |
IRF4 |
More about : IRF4 |
| Long gene name: |
interferon regulatory factor 4 |
| Synonyms gene: |
MUM1 |
| Synonyms: |
LSIRF |
| Locus: |
6p25, 3 |
| Discovery year: |
1996-05-31 |
| GenBank acession: |
U52682 |
| Entrez gene record: |
3662 |
| Pubmed identfication: |
8921401 18417578 |
| Havana BLAST/BLAT: |
OTTHUMG00000016294 |