| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
p63 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the p63 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This p63 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9H3D4 |
| Purity: |
Antigen affinity |
| Description: |
It has been found that the combined loss of TP63 and p73 results in the failure of cells containing functional p53 to undergo apoptosis in response to DNA damage, It is a member of the p53 family of transcription factors, It is an essential regulator of stem cell maintenance in stratified epithelial tissues, TP63 has been mostly restricted to its apoptotic function and more recently as the guardian of oocyte integrity, TP63 is also critical for maintaining the progenitor-cell populations that are necessary to sustain epithelial development and morphogenesis, This gene encodes for two main isoforms by alternative promoters (TAp63 and dNp63), also known as TP73L is a protein that in humans is encoded by the TP63 gene, Tumor protein p63 (TP63) |
| Immunogen: |
Human partial recombinant protein (AA 311-680) was used as the immunogen for this p63 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the p63 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
p63 |
| Short name: |
p63 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
p63 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
52353 |
| Gene: |
TPRG1LP1 |
More about : TPRG1LP1 |
| Long gene name: |
tumor protein p63 regulated 1 like pseudogene 1 |
| Locus: |
19q13, 43 |
| Discovery year: |
2016-07-28 |
| Entrez gene record: |
100130490 |