| Long name: |
p63 Primary Polyclonal Antibody |
| Also known as: |
p63 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
p63 |
| Specificity: |
This is a highly specific antibody against p63 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
370-420/680 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p63 protein |
| Gene ID number: |
8626 |
| Swiss Prot: |
Q9H3D4 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activates transcription of the p21 promoter, Involved in Notch signaling by probably inducing JAG1 and JAG2, Isoform 2 activates RIPK4 transcription, May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes, Plays a role in the regulation of epithelial morphogenesis, Required for limb formation from the apical ectodermal ridge, The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity, The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm, Acts as a sequence specific DNA binding transcriptional activator or repressor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
B(p51A), B(p51B), CUSP, Chronic ulcerative stomatitis protein, EEC3, KET, Keratinocyte transcription factor KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP63, TP73L, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like, p4, p51, p53CP, p63, p73H, p73L, AIS |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
p63 |
| Short name: |
p63 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
p63 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
52353 |
| Gene: |
TPRG1LP1 |
More about : TPRG1LP1 |
| Long gene name: |
tumor protein p63 regulated 1 like pseudogene 1 |
| Locus: |
19q13, 43 |
| Discovery year: |
2016-07-28 |
| Entrez gene record: |
100130490 |