| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Annexin A1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Annexin A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Annexin A1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
301 |
| Purity: |
Antigen affinity |
| Description: |
ANXA1 protein has an apparent relative molecular mass of 40 kDa, It belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35, It is mapped to 9q21, Lower peptide concentrations possibly found in inflammatory situations elicit Ca(2+) transients without fully activating the mitogen-activated protein kinase pathway, These findings identified ANXA1 peptides as novel, This causes a specific inhibition of the transendothelial migration of neutrophils and a desensitization of neutrophils toward a chemoattractant challenge, also known as Lipocortin I or Annexin A1, endogenous FPR ligands and established a mechanistic basis of ANXA1-mediated antiinflammatory effects, is a protein that in humans is encoded by the ANXA1 gene, with phospholipase A2 inhibitory activity, 000 and are preferentially located on the cytosolic face of the plasma membrane, 000 to 40, 13, ANXA1 |
| Immunogen: |
Human partial recombinant protein (AA 2-346) was used as the immunogen for this Annexin A1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Annexin A1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Annexin A1 |
| Short name: |
Annexin A1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Annexin A1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
514 |
| Gene: |
ANX1 |
More about : ANX1 |
| Long gene name: |
annexin A1 |
| Synonyms gene: |
LPC1 |
| Synonyms: |
ANXA1 |
| Locus: |
9q21, 13 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X05908 |
| Entrez gene record: |
301 |
| Pubmed identfication: |
2936963 |
| RefSeq identity: |
NM_000700 |
| Classification: |
Endogenous ligands Annexins |
| Havana BLAST/BLAT: |
OTTHUMG00000020016 |