| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Annexin A1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Annexin A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Annexin A1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P04083 |
| Purity: |
Antigen affinity |
| Description: |
Annexin I acts through the formyl peptide receptor on human neutrophils, Annexin I gene, In two lipocortins(I and II) a short amino-terminal sequence distinct from the core structure has potential regulatory functions which are dependent on its phosphorylation state, Mouse Lipo1 gene spans about 17 kb and is divided into 13 exons, Peptides derived from the unique N-terminal domain of annexin I serve as FPR ligands and trigger different signaling pathways in a dose-dependent manner, The gene in the mouse encodes a protein of 346 amino acid residues, These proteins are though to control the biosynthesis of the potent mediators of inflammation, also known as lipocortin I(Lipo1), belongs to the family of annexins, is located on mouse chromosome 19, mapped to 9q11-q22, prostaglandins and leukotrienes, Annexin I |
| Immunogen: |
An amino acid sequence from the N-terminus of human Annexin A1 (MVSEFLKQAWFIENEEQEYVQT) was used as the immunogen for this Annexin A1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Annexin A1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Annexin A1 |
| Short name: |
Annexin A1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Annexin A1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
514 |
| Gene: |
ANX1 |
More about : ANX1 |
| Long gene name: |
annexin A1 |
| Synonyms gene: |
LPC1 |
| Synonyms: |
ANXA1 |
| Locus: |
9q21, 13 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X05908 |
| Entrez gene record: |
301 |
| Pubmed identfication: |
2936963 |
| RefSeq identity: |
NM_000700 |
| Classification: |
Endogenous ligands Annexins |
| Havana BLAST/BLAT: |
OTTHUMG00000020016 |