| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Beclin 1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Beclin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Beclin 1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
8678 |
| Purity: |
Antigen affinity |
| Description: |
Beclin 1 and its binding partner class III phosphoinositide 3-kinase (PI3K), It has been found that Beclin 1 can promote autophagy in autophagy-defective yeast with a targeted disruption of apg6/vps30, Schizophrenia is associated with low levels of the protein in the hippocampus of the affected which causes diminished autophagy which in turn results in increased neuronal cell death, This gene participates in the regulation of autophagy and has an important role in development, also known as also known as ATG6 or VPS30 is a protein that in humans is encoded by the BECN1 gene, also named Vps34, and in human MCF7 breast carcinoma cells, and neurodegeneration, are required for the initiation of the formation of the autophagosome in autophagy, tumorigenesis, Beclin 1 |
| Immunogen: |
Human partial recombinant protein (AA 1-354) was used as the immunogen for this Beclin 1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Beclin 1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Beclin 1 |
| Short name: |
Beclin 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Beclin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
51330 |
| Gene: |
BECN1P2 |
More about : BECN1P2 |
| Long gene name: |
beclin 1 pseudogene 2 |
| Synonyms gene name: |
autophagy related, beclin 1, pseudogene 2 |
| Locus: |
6q13 |
| Discovery year: |
2014-10-03 |
| Entrez gene record: |
100420149 |
| RefSeq identity: |
NG_025950 |
| Havana BLAST/BLAT: |
OTTHUMG00000014998 |