| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Beclin 1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Beclin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Beclin 1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q14457 |
| Purity: |
Antigen affinity |
| Description: |
A 2, ATG6, Beclin 1 and its binding partner class III phosphoinositide 3-kinase (PI3K), Coiled-coil myosin-like BCL2-interacting protein, Immunoperoxidase staining of human hippocampus and frontal cortex sections revealed Beclin 1 immunoreactivity in many neurons throughout these regions, In some tissues, It protects against infection by a neurovirulent strain of Sindbis virus that is known to overcome the protective effects of Bcl2, Liang et al, Northern blot analysis of mouse and adult human tissues revealed widespread expression, Protein GT197, The gene encodes a novel 450-amino acid protein containing a coiled-coil region, VPS30, additional 1, also known as BECN1, also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy, as well as in some glial cells, autophagy-related gene 6 (ATG6), showed that Beclin 1 reduced Sindbis virus replication in mouse brain and reduced Sindbis virus-induced cell death in mouse brain, suggesting the presence of alternatively spliced transcripts, within which it has limited homology to myosin-like proteins, 2-kb transcript was present at highest levels in human skeletal muscle and at detectable levels in all tissues examined, 4-kb transcripts were observed, 7- and 1, Bellini-1 is a protein that in humans is encoded by the BECN1 gene |
| Immunogen: |
mouse and rat), Amino acids 222-237 (LDQEEAQYQREYSEFK) were used as the immunogen for this Beclin 1 antibody (100% homologous in human |
| Storage: |
After reconstitution, Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, Store the lyophilized Beclin 1 antibody at 4oC |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Beclin 1 |
| Short name: |
Beclin 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Beclin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
51330 |
| Gene: |
BECN1P2 |
More about : BECN1P2 |
| Long gene name: |
beclin 1 pseudogene 2 |
| Synonyms gene name: |
autophagy related, beclin 1, pseudogene 2 |
| Locus: |
6q13 |
| Discovery year: |
2014-10-03 |
| Entrez gene record: |
100420149 |
| RefSeq identity: |
NG_025950 |
| Havana BLAST/BLAT: |
OTTHUMG00000014998 |